Browsing by Subject "Optimal designs (Statistics)"

Now showing items 1-4 of 4

    • Ds-Optimal Design for Model Discrimination in a Probit Model 

      Liu, Ruifeng (North Dakota State University, 2014)
      In toxicology studies, dose response functions with a downturn at higher doses are often observed. For such response functions, researchers often want to see if the downturn of the response is signifcant. A probit model ...

    • Optimal Designs for the Hill Model with Three Parameters 

      Dockter, Travis Jon (North Dakota State University, 2012)
      Optimal designs specify design points to use and how to distribute subjects over these design points in the most efficient manner. The Hill model with three parameters is often used to describe sigmoid dose response ...

    • Robust D-Optimal Design for Multiple Nominal Parameter Values under the 5PL-1P Model 

      Liang, Cuiping (North Dakota State University, 2018)
      A robust D-optimal design that works well for multiple nominal parameter values is presented in this paper. In general, D-optimal design works very well for estimating the model parameters, but it is very sensitive to ...

    • Robust D-Optimal Design for Response Functions with a Downturn 

      Carter, Jessica Anne (North Dakota State University, 2013)
      Researchers studying dose-response relationships must allocate limited resources to design points in order to maximize the information gained from the study. D-optimal design is a well-described design that works efficiently ...