An estimated 2.3 million hectares are salt-affected in North Dakota (Brennan and Ulmer, 2010), a number increasing due to land management, climate, and crop choice. As a result, yield reductions are noted for salt-sensitive crops such as soybean [Glycine max (L.) Merr] and corn (Zea Mays L.). The objective of this greenhouse study was to assess soybean and corn response to salinity, using sulfate based salts. Soybean leaf area, plant mass, and height decreased by 66, 59, and 47%, respectively, across a salinity gradient ranging from an EC1:1 of 0.4 to 4.1 dS m-1. Corn mass and height decreased by 42 and 26%, respectively, root length and mass also decreased by 44 and 37%, respectively from an EC1:1 0.8 to 5.3 dS m-1. Thus, planting soybean and corn on salt-affected soils in North Dakota will result in overall decreased productivity for both crops even at low levels of salinity.