This purpose of this thesis is to emphasize the importance of the biophysical connection between the human psyche and the environment. In theory, these elements can coexist to manipulate the relationship between design and emotion. This emotional response to the built environment creates a biophysical relationship between humans and their environment, in return, creating an everlasting experience. Architecture is a realm of design that guides the user on their journey through physical limitation. This limitation can be manipulated to induce an emotional narrative influencing what each occupant does, experiences and remembers. This opportunity to promote an emotional response is the realm of design that needs to be considered when establishing a theory of connectivity between the human neurological state and the built environment.