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Attempted Total Syntheses of a Novel Lycopodine-Class Alkaloid and (R)-Myricanol, Compounds for the Treatment of Alzheimer's Disease
(North Dakota State University, 2013)
Alzheimer's Disease (AD) is a significant challenge to both the pharmaceutical world as well as the synthetic organic chemistry world. One of the most important problems in this field is the lack of a unified approach to ...
Stereospecific Photochemical Transformations Involving Axially Chiral Acrylanilides and a-Oxoamides
(North Dakota State University, 2013)
Asymmetric photochemical transformations have been under-explored due to the ineffectiveness of conventional methodologies/reagents/catalysts (point chiral auxiliaries and inductors) that were generally employed for thermal ...
Developing Platform Chemicals from Renewable Resources
(North Dakota State University, 2013)
The Department of Energy has listed 5-hydroxymethylfurfural (HMF) and 2,5-furandicarboxylic acid (FDCA) as two of the twelve building blocks derived from cellulosic biomass. HMF can serve as a renewable platform for the ...
Synthesis and Antioxidant, Anticancer, and Antimicrobial Activities of Palmityl Ester Derivative of Carnosic Acid
(North Dakota State University, 2013)
Carnosic acid (CA) along with carnosol (CAR) is the strongest phenolic diterpene antioxidants (PDAs) present in rosemary plant. However, CA has low antioxidant activity in emulsion-type food system due to its polar nature. ...
Lung Mucosal Response to Repeated Inhalational Insults with Immunomodulatory Agents in a Murine Model of Fungal Asthma: Airway Epithelium Takes the Center Stage
(North Dakota State University, 2013)
Asthma is a debilitating disease of the lungs affecting 235 million people worldwide. Fungus-associated asthma leads to a particularly severe type of disease, and exposure to environmental fungi and their products is ...