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Item The Acute Effects of L-Arginine Supplementation on Flow-Mediated Dilation after Resistance Training to Fatigue(North Dakota State University, 2017) Streeter, DanielThe purpose of this study was to determine the effects of acute L-arginine supplementation on the endothelial health in healthy adults by assessing flow-mediated dilation (FMD) and cardiovascular indicators both before and after resistance exercise to fatigue. Thirty (15 male, 15 female) physically active healthy participants (mean ± SD: age 20.4 ± 1.8 years, height 176.9 ± 10.2 cm, body mass 76.0 ± 12.2 kg) volunteered for a randomized, cross-over, double-blind, placebo controlled clinical trial. Participants completed five sets of isokinetic elbow extension/flexion exercise after consumption of either placebo or 3 g L-arginine one hour prior. Baseline brachial artery diameter significantly increased post FMD (p<0.001), post-exercise (p<0.001), post-exercise FMD (p<0.001). There was no significant supplement effect on FMD (p=0.179). The increase in brachial diameter due to fatiguing exercise was not enhanced by acute supplementation with L-arginine nor did supplementation alter FMD responses after exercise.Item The effects of an acute session of blood flow restriction exercise on autonomic modulation(North Dakota State University, 2024) Garner, AndrewPURPOSE: How an acute training session of blood flow restriction (BFR) exercise affects autonomic modulation during a unilateral knee extension exercise. METHODS: Fourteen physically active males completed three different sessions while performing a unilateral knee extension exercise. The dependent variables measured: Heart rate variability (HRV), muscle oxygen saturation (SmO2), and rating of perceived exertion (RPE). Repeated measures ANOVAs were used to analyze HRV and SmO2 data. A paired t-test was used to analyze RPE data. RESULTS: Significant time-effect differences were found in lnRMSSD, lnHF, and lnLF at baseline to 15 minutes post-exercise and 15 to 30 minutes post-exercise (P < 0.05). Time and group-effect differences were significant in SmO2%, oxygenated, and deoxygenated hemoglobin in the vastus lateralis (VL) muscle in BFR compared to control (P < 0.05). RPE increased when BFR was applied (P < 0.05). CONCLUSION: Exercise protocol may need to be altered to show autonomic modulation changes.