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Item Rise of Melatonin Supplementation: Results, Side Effects, and Concerns(North Dakota State University, 2024) Ensign, LoraThis paper explores the rising interest in melatonin supplements, highlighting their potential benefits for sleep quality amongst concerns about safety and regulation. While melatonin naturally regulates sleep-wake cycles, synthetic supplements offer convenience but pose risks such as interactions with medications and labeling errors. Informed decision-making, including consulting healthcare professionals, is essential to maximize benefits while minimizing risks. Despite promising results, further research is needed to fully understand melatonin's effects. Therefore, a cautious and informed approach is crucial for its effective and safe use in promoting overall wellness.