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Gene Regulation in Biofilms
(North Dakota State University, 2011)
Sessile bacterial communities which form on the solid surface or solid-liquid interface
are known as biofilms. Both single species and multispecies biofilms are characterized
by an extracellular matrix of polymeric ...
Physical and Chemical Treatments for Bacterial Biofilms
(North Dakota State University, 2014)
Physical and chemical treatments have been investigated for the treatment to remove biofilms. This thesis examines the problem of the removal and prevention of biofilms by: (i) using a water jet to determine biofilm stability ...
Variability in Plant Growth Promoting Properties Among Clinical and Environmental Isolates of Stenotrophomonas Maltophilia
(North Dakota State University, 2015)
Stenotrophomonas maltophilia has both negative and positive attributes by being a human pathogen and plant growth promoting rhizobacterium. This study sought to determine if environmental and clinical isolates of S. ...
An Overview of SARS-CoV-2 Covid-19: Epidemiology, Origin, and Pathology
(North Dakota State University, 2020)
Following SARS (years 2002-2003) and MERS (year 2012) outbreaks, humans have faced a new highly contagious virus, SARS-COV-2, which began late 2019 and resulted in a pandemic (COVID-19 pandemic). The disease has been spread ...
Brucellosis Epidemiology, Virulence Factors, Control and Molecular Targets to Prevent Bacterial Infectious Diseases
(North Dakota State University, 2012)
Brucellosis is a bacterial zoonosis that infects both professional phagocytic and nonphagocytic cells in the hosts. Brucella intracellular survival is important for its virulence. In a study to establish the seroprevalence ...
Genetic Disruption of VIP Signaling Alters Intestinal Microbial Structure and Immunity
(North Dakota State University, 2018)
Vasoactive intestinal peptide (VIP) regulates clock gene expression in the brain that synchronizes diurnal feeding behaviors in mammals. In the gastrointestinal (GI) tissues, VIP influences host nutrient absorption from ...
Glycan Triggers of Life Cycle Development in the Apicomplexan Parasite Cryptosporidium
(North Dakota State University, 2017)
Cryptosporidium is an apicomplexan parasite that causes the diarrheal disease cryptosporidiosis, an infection that can become chronic and life threating in immunocompromised and malnourished individuals. Development of ...
Heterogeneity in Phenotypic Response of Foodborne Pathogens to Control Measures
(North Dakota State University, 2019)
Foodborne pathogens are estimated to cause 48 million foodborne illnesses through consumption of contaminated food annually. Designing efficient control measures is vital to reducing foodborne illnesses. The modern trend ...
Investigations in Asthma Heterogeneity: The Roles of Aspergillus Fumigatus-Derived Eicosanoid Synthases and Occupational Exposures to Grain Dusts on the Development of Fungal Allergic Asthma
(North Dakota State University, 2013)
Allergic asthma is an inflammatory syndrome of the respiratory system which changes the airway wall architecture. Using an aeroallergen, murine model of A. fumigatus-mediated asthma, the two studies herein examine the ...
Biofilm Formation of Escherichia coli from Surface Soils is Influenced by Variation in Cell Envelope, Iron Metabolism, and Attachment Factor Genes
(North Dakota State University, 2018)
Biofilm formation may increase survival and persistence of Escherichia coli in the highly variable conditions of soil environments, though it remains unknown the extent variation in biofilm formation affects survival. We ...