Browsing NDSU Theses & Dissertations by Author "Kulkarni, Prajakta"
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Design and Development of Tumor Microenvironment Responsive PEGylated Nanoparticles for Drug Delivery to Cancerous Solid Tumors
Kulkarni, Prajakta (North Dakota State University, 2016)Rapid growth of cancerous cells creates a biochemically distinct microenvironment in solid tumors. Leaky vasculature, lower pH, increased levels of proteolytic enzymes, hypoxia serve as hallmarks of tumor tissues. These ...