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Apoptosis-Inducing Factor Mediates Metabolism and Oxidative Stress Signaling through Functionally Uncoupled Mechanisms to the Benefit of Tumorigenesis
(North Dakota State University, 2019)
Cancer is one of the leading causes of death in the world, arising when cells accumulate genomic mutations that render them incapable of controlling their own proliferation and survival. While substantial improvements in ...
Understanding the Interaction Between Enzymes and Nanomaterials
(North Dakota State University, 2019)
The rapid development of nanoparticles (NPs) has impacted many fields including energy efficiency, material science, biosensing, and medical therapeutics. Recently, NPs have been utilized to immobilize enzymes. The so-formed ...
Mechanistic Studies on the Methionine Aminopeptidase and Peptide Deformylase Catalyzed Reactions
(North Dakota State University, 2013)
In the search for novel antibiotic and therapeutic targets, methionine aminopeptidase (MetAP) and peptide deformylase (PDF) have recently been identified as eminently compelling. These enzymes are involved in the ...
Micro-/Nano- Materials Based Ultrasensitive Lateral Flow Nucleic Acid Biosensors
(North Dakota State University, 2017)
Ultrasensitive detection of nucleic acids plays a very important role in the field of molecular diagnosis for the detection of various diseases. Lateral flow biosensors (LFB) are convenient, easy-to-use, patient friendly ...
Exciton Diffusion, Transport, and Localization in Conjugated Polymers
(North Dakota State University, 2013)
Conjugated polymers are wide bandgap semiconductors which have a series of conjugated π-orbitals that extend along the polymer ‘backbone’. The π-orbital conjugation can be disrupted by twisting of the polymer, affecting ...
Identification of Novel RPA-Protein Interactions Using the Yeast Two Hybrid Assay and Identification of Regions Important for Interaction Between RPA and Rad24
(North Dakota State University, 2013)
Replication Protein A (RPA) [Replication Factor A (RFA) in yeast] is an ssDNA binding protein
composed of Rpa1, Rpa2, and Rpa3 and involved in numerous DNA processing pathways such as
Replication, Recombination, and Repair. ...
Infrared Diode Laser Spectroscopic Study of Combustion Related Kinetics
(North Dakota State University, 2016)
In the introduction section background into the subject of combustion chemistry is presented. The topics included are combustion mechanisms, combustion pollutants, and infrared absorption spectroscopy. Chapter two describes ...
Design and Selling Recycled Fashion: Acceptance of Upcycled Secondhand Clothes by Female Consumers, Age 25-65
(North Dakota State University, 2014)
Fast fashion offers low prices and lots of choices with the opportunity to binge on fashion. Wardrobes are overflowing, and consumers are considering the options for disposal and recycling of their clothes. Upcyling is one ...
Supply Chain Management and Lean Six Sigma in a Retail Environment
(North Dakota State University, 2013)
This qualitative research evaluated the as-is supply chain management and logistics retail processes of Dell, a manufacturing company that also has retail operations globally. Dell has an online channel capable of serving ...
Retail Change: A Look at the Past, Present, and Future
(North Dakota State University, 2014)
The retail industry has evolved over time and has had constant change. Retailers adjust to accommodate with the changes, and those that are able to change with the times are more likely to be successful. The history of ...