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Now showing items 1841-1850 of 4247
Understanding Binding-Induced Disorder-to-Order And Conformational Transitions in Proteins that Regulate Autophagy
(North Dakota State University, 2018)
Autophagy, a cellular homeostasis process that degrades and recycles cytosolic contents, is regulated at various stages by protein interactions. BECN1 regulates autophagy through interactions with diverse proteins via ...
Delineating Signaling Mechanisms Involved in Lymphocyte Chemotaxis, Immune Homeostasis and Allergic Asthma
(North Dakota State University, 2015)
The vasoactive intestinal peptide (VIP) signaling axis constitutes VIP and its two G protein coupled receptors (GPCR) termed vasoactive intestinal/pituitary adenylate cyclase activating polypeptide (VPAC) 1 and 2. This ...
Characterization of RPA2 N-terminal Function in the DNA Damage Response in Saccharomyces Cerevisiae
(North Dakota State University, 2015)
In response to DNA damage, two general but fundamental processes occur in the
cell: (1) a DNA lesion is recognized and repaired, and (2) concomitantly, the cell halts
the cell cycle to provide a window of opportunity for ...
Fabrication and Characterization of Antifungal Essential Oil-In-Water Nanoemulsion Delivery System Targeting Fusarium Graminearum In Vitro and During the Malting Process
(North Dakota State University, 2019)
Fusarium mycotoxins represent the most food safety concern for the malting industry. The complete prevention of Fusarium mycotoxins in the grains by limiting toxigenic fungi in the field and during storage is not practical. ...
Synthesis of Precursors to Non-isocyanate Polyurethanes
(North Dakota State University, 2018)
Biobased diamines are excellent precursors for the synthesis of non-isocyanate polyurethanes (NIPUs). We have prepared several biobased diamines using three different reactions for their synthesis. In the first method, we ...
Functionalization of Heterocycles: A Metal Catalyzed Approach via Allylation and C-H Activation
(North Dakota State University, 2018)
The central core of many biologically active natural products and pharmaceuticals contain N-heterocycles, the installation of simple/complex functional groups using C-H/N-H functionalization methodologies has the potential ...
Synthesis and Design of Thiophene Materials: Effects of Ring Fusion and Metal Coordination
(North Dakota State University, 2019)
Conjugated organic materials comprise a field of materials chemistry focused on the development of semiconducting organic plastics, popular applications of which are plastic solar cells and display technologies. One of the ...
Thiazole vs. Thiophene: Heterocycle Effects on the Properties of Fused-Ring Conjugated Materials
(North Dakota State University, 2017)
Conjugated polymers and related molecular materials comprise a field of materials chemistry focused on the development of semiconducting organic plastics that find use in applications such as organic solar cells and organic ...
Synthesis, Characterization, and Application of Low and Reduced Band Gap Thieno[3,4-b]pyrazine-based Materials
(North Dakota State University, 2013)
Conjugated polymers are a class of materials receiving significant interest due to their unique combination of optical and electronic properties found in inorganics with the flexibility and processability of traditional ...
The Development and Use of Chiral 4-Dimethylaminopyridine-N-Oxide as an Organocatalyst
(North Dakota State University, 2018)
Organocatalysis is a field that has bloomed over the last decades. With the field’s promise of being able to mimic nature and afford products in a synergistic manner to traditional Lewis acid catalysis, several interesting ...