The objective of this study is to examine the effects of exchange rate on bilateral trade between the United States and South Korea. The panel data for each commodity group over the period from 1989 to 2013 are employed for this study. Export supply model and import demand model are developed to analyze the effects of significant factors on the three trade sectors: agriculture, mid technology, and high technology. Random effect method is chosen in this study. The result indicates that exchange rate has an important role for U.S. mid and high technology trade with South Korea and exchange rate volatility has positive effects on U.S. mid and high technology exports to South Korea. Intra-industry trade is affected by exchange rate more than inter-industry trade.