Background: There is limited quantitative research on joint space measurements to support the use of Kinesio Tape Space Correction Method®. There is limited to no research regarding the use of diagnostic ultrasound to take a measurement of specific joint spaces. Methods: 32 subjects with bilaterally-healthy knees, no reported surgeries or reported allergies to Kinesio Tape®, reported their dominant knee to the researcher, who then measured their patellofemoral joint space with diagnostic ultrasound. Measurements were taken, the Kinesio Tape Space Correction Method® was applied, and left on for 10 minutes with the patient in a non-weight-bearing position. After 10 minutes, the joint space was re-measured. Results: There was a statistically significant difference (t[31]=2.823, p=.008) between pre-and post-taped patella to femur measurements. Conclusion: Results indicate that patellofemoral joint spaces can be increased by the Kinesio Tape Space Correction Method® after 10 minutes of application. Keywords: Kinesio Tape®, Diagnostic Ultrasound, Patellofemoral Joint Space