As mobile healthcare applications are becoming more and more popular, it brings patients a more convenient way to self-management and communicating remotely compare to the traditional healthcare system. This paper introduces a healthcare mobile application of diabetes self-management that designed, developed, and tested by professor Li’s research team. The application is going to be used by American Indian diabetes patients in Lower Sioux Tribe. The application enabled patients to self-monitor their nutrients intake and health information. The social chatting and education functionality allow users to communicate and get educated remotely. By combining the advantages of both mobile health application and self-management systems together, the application provides great benefits especially for chronic diseases like diabetes. It is thrilling to see more and more implementations of mobile health self-management applications and improve the treatment of chronic disease.