Larry (Lawrence) Reynolds - Thesis Committee
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Recent Submissions
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Quantifying Seasonal Variation in Physiological Condition of Adult Franklin's Gull (Luecophaeus Pipixcan) during Nesting
(North Dakota State University, 2011)Understanding seasonal variation in adult physiological condition is important for developing hypotheses on how nest initiation, adult condition, chick development and recruitment are related in Franklin's gull and other ... -
Genetic Disruption of VIP Signaling Alters Intestinal Microbial Structure and Immunity
(North Dakota State University, 2018)Vasoactive intestinal peptide (VIP) regulates clock gene expression in the brain that synchronizes diurnal feeding behaviors in mammals. In the gastrointestinal (GI) tissues, VIP influences host nutrient absorption from ... -
Biological Evaluation of the Associations Between Animal Size, Feeding Behavior, Blood Metabolites and Feed Efficiency in Beef Cattle
(North Dakota State University, 2017)The biological variation in feed efficiency is regulated by multiple physiological mechanisms relevant to energy use in livestock species. The current study examined the associations between body composition, feeding ... -
Effects of Maternal Nutrition on Fructose, Glucose, and Cationic Amino Acid Transporter Expression in Bovine Utero-Placental Tissues from Days 16 to 50 of Gestation
(North Dakota State University, 2016)Poor Maternal nutrition has been implicated to reduce nutrient transport to the conceptus. Therefore, we hypothesized that maternal nutrition and day of gestation would impact mRNA expression of nutrient transporters GLUT1, ... -
The Impact of Digestive Enzymes in the Ruminant Animal
(North Dakota State University, 2016)Understanding the enzymatic activity in ruminant digestive systems is essential for securing adequate growth, reproduction and overall metabolism. In order to evaluate the impact of various nutritional sources and dietary ... -
Structural Studies of BECN1, A Key Autophagy Protein, and Intrinsically Disordered Regions in Autophagy Proteins
(North Dakota State University, 2016)Autophagy, a conserved catabolic process required for cellular homeostasis in eukaryotes, is regulated by many proteins. The central goal of my doctoral research is to investigate conformational flexibility of autophagy ... -
Maternal Nutritional Plane and Endogenous Retroviral Gene Elements, Pregnancy Hormones, and Placental Vascularity and Angiogenic Factors during the Establishment of Pregnancy in Beef Cattle
(North Dakota State University, 2016)In order to meet the projected food demands by 2050, animal agriculture must increase production of animal products on the same or decreased land area through increased efficiency. Early gestation is one area to increase ... -
Arginine Supplementation Strategies during Gestation: Impacts on Dams and Offspring
(North Dakota State University, 2015)We hypothesize rumen-protected arginine supplementation during gestation will mitigate deleterious offspring effects caused by undernutrition. Experiment 1: non-pregnant ewes were supplemented with rumen-protected arginine ... -
Implementation of Fourier Repetitive Control in Labview
(North Dakota State University, 2014)This thesis presents position control as well as current (torque) control of a DC servo motor with a periodic input. Position control is achieved by using Fourier repetitive control scheme. Simulation on position control ... -
Growth Hormone Mediated Regulation of Osmoregulation in Euryhaline Teleosts
(North Dakota State University, 2014)Within the multitude of fish species that exist on our planet, there are a certain number that possess the unique ability to live in both freshwater (FW) and seawater (SW) environments. This ability, known as euryhalinity, ... -
The Discovery of a Novel Growth Hormone Receptor and the Nutritional Regulation of the Growth Related Actions of Growth Hormone
(North Dakota State University, 2017)The growth hormone (GH) family peptides such as GH, prolactin (PRL), and somatolactin (SL) regulate a wide array of physiological actions including but not limited to growth, metabolism, osmoregulation, and lipolysis. These ... -
Impacts of Supplemental Arginine on Ewe Reproductive Performance
(North Dakota State University, 2014)The objective of this study was to determine the effects of injectable and oral arginine (Arg) supplementation provided 14 d post-breeding on reproductive performance of fall lambing ewes. Upon estrus detection (d 0) ewes ... -
Effects of Corn Condensed Distillers Solubles Supplementation on Intake, Performance, Rate and Site of Digestion, and Ruminal Fermentation in Cattle Consuming Forage-Based Diets
(North Dakota State University, 2015)Two studies were conducted to determine effect of feeding method and level of corn condensed distillers solubles supplementation on performance of beef cows fed forage-based diets and effects on digestibility and ruminal ... -
Biophysical Studies of Ligand Binding to Human Histone Deacetylase-8
(North Dakota State University, 2014)Due to an involvement in various patho-physiological conditions, human histone deacetylases (HDACs) are high priority drug targets for the treatment of several diseases, such as cancer, heart failure, neurodegeneration, ... -
Impacts of Beef Cow Nutrition on Conceptus Development
(North Dakota State University, 2013)Two experiments were conducted to determine the effect of maternal nutrient restriction followed by realimentation during early to mid-gestation on uterine blood flow (BF), maternal performance, and conceptus development ... -
Effects of Environmental Estrogens on the Growth Hormone-Insulin-Like Growth Factor System in Rainbow Trout (Oncorhynchus Mykiss)
(North Dakota State University, 2013)The increasing production, use, and disposal of an expanding array of chemicals that enter the environment pose a serious threat to terrestrial and aquatic animals, as well as to humans. Fish in aquatic habitats are exposed ... -
Influence of Maternal Nutrient Intake on Placental Vascular Function in Pregnant Beef Cows
(North Dakota State University, 2014)We hypothesized that global maternal nutrient restriction during early and mid-gestation followed by realimentation in pregnant beef cows would alter placental arterial vascular function. We tested changes in placental ... -
Augmented Expression of Apelin/APJ in the Paraventricular Nuclei of Rats after Myocardial Infarction
(North Dakota State University, 2012)Heart failure (HF) is a disease condition in which insufficient blood is pumped through the body. The pathophysiology of HF is multisystematic and includes a collection of different responses to compensate for the inability ... -
The Role of Platelet-Derived Growth Factor Receptor Signaling in Medulloblastoma Metastasis
(North Dakota State University, 2013)Medulloblastoma is the most common brain tumor in children and one third of the patients remain incurable. Tumor metastasis is one of the primary reasons for its high mortality rate. Despite evidence of overexpression of ... -
An Insilico Design of Nanoclay Based Nanocomposites and Scaffolds In Bone Tissue Engineering
(North Dakota State University, 2016)A multiscale in silico approach to design polymer nanocomposites and scaffolds for bone tissue engineering applications is described in this study. This study focuses on the role of biomaterials design and selection, ...
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