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Investment Behavior Analysis Based on Tail Risk Management
(North Dakota State University, 2018)
As behavioral finance is becoming more prevalent in academic area, a study is worth conducting to pinpoint investors’ preference through managing tail risk of asset portfolios. This study investigates investors’ investment ...
Testing Parallelism for the Four-Parameter Logistic Model with D-Optimal Design
(North Dakota State University, 2018)
In order to determine the potency of the test preparation relative to the standard preparation, it is often important to test parallelism between a pair of dose-response curves of reference standard and test sample. Optimal ...
Investigating Statistical vs. Practical Significance of the Kolmogorov-Smirnov Two-Sample Test Using Power Simulations and Resampling Procedures
(North Dakota State University, 2018)
This research examines the power of the Kolmogorov-Smirnov two-sample test. The motivation for this research is a large data set containing soil salinity values. One problem encountered was that the power of the ...
A Comparison of Methods Taking into Account Asymmetry when Evaluating Differential Expression in Gene Expression Experiments
(North Dakota State University, 2018)
Gene expression technologies allow expression levels to be compared across treatments for thousands of genes simultaneously. Asymmetry in the empirical distribution of the test statistics from the analysis of a gene ...
Adaptive Two-Stage Optimal Design for Estimating Multiple EDps under the 4-Parameter Logistic Model
(North Dakota State University, 2018)
In dose-finding studies, c-optimal designs provide the most efficient design to study an interesting target dose. However, there is no guarantee that a c-optimal design that works best for estimating one specific target ...
Exploring Associations between Lifestyles and Metabolic Syndrome in Middle-Age Chinese Population
(North Dakota State University, 2018)
Nowadays the prevalence of Metabolic Syndrome (MetS) affects many middle-age people in China. MetS is associated with the risk of type 2 diabetes and cardiovascular disease. Identifying the potential risk factors contribute ...
A Visualization Technique for Course Evaluations and Other Likert Scale Data
(North Dakota State University, 2018)
Course evaluation is one of the primary ways of collecting feedback from students at NDSU. Since almost every student in every course submits one at the end of the semester, it generates a lot of data. The data is summarized ...
Integrative Data Analysis of Microarray and RNA-seq
(North Dakota State University, 2018)
Background: Microarray and RNA sequencing (RNA-seq) are two commonly used high-throughput technologies for gene expression profiling for the past decades. For global gene expression studies, both techniques are expensive, ...
Robust D-Optimal Design for Multiple Nominal Parameter Values under the 5PL-1P Model
(North Dakota State University, 2018)
A robust D-optimal design that works well for multiple nominal parameter values is presented in this paper. In general, D-optimal design works very well for estimating the model parameters, but it is very sensitive to ...
Comparative Analysis of Traditional and Modified DECODE Method in Small Sample Gene Expression Experiments
(North Dakota State University, 2018)
Background: The DECODE method integrates differential co-expression and differential expression analysis methods to better understand biological functions of genes and their associations with disease. The DECODE method ...