Browsing Statistics Doctoral Work by Title
Now showing items 11-30 of 34
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Identification of Differentially Expressed Genes When the Distribution of Effect Sizes is Asymmetric in Two Class Experiments
(North Dakota State University, 2017)High-throughput RNA Sequencing (RNA-Seq) has emerged as an innovative and powerful technology for detecting differentially expressed genes (DE) across different conditions. Unlike continuous microarray data, RNA-Seq data ... -
Integrative Data Analysis of Microarray and RNA-seq
(North Dakota State University, 2018)Background: Microarray and RNA sequencing (RNA-seq) are two commonly used high-throughput technologies for gene expression profiling for the past decades. For global gene expression studies, both techniques are expensive, ... -
Measuring Performance of United States Commercial and Domestic Banks and its Impact on 2007-2009 Financial Crisis
(North Dakota State University, 2019)In the analysis of efficiency measures, the statistical Stochastic Frontier Analysis (SFA) and linear programming Data Envelopment Analysis (DEA) estimators have been widely applied. This dissertation is centered around ... -
Model Validation and Diagnostis in Right Censored Regression
(North Dakota State University, 2013)When censored data are present in the linear regression setting, the Expectation-Maximization (EM) algorithm and the Buckley and James (BJ) method are two algorithms that can be implemented to fit the regression model. We ... -
Nonparametric Test for Nondecreasing Order Alternatives in Randomized Complete Block and Balanced Incomplete Block Mixed Design
(North Dakota State University, 2020)Nonparametric tests are used to test hypotheses when the data at hand violate one or more of the assumptions for parametric tests procedures. The test is an ordered alternative (nondecreasing) when there is prior information ... -
Nonparametric Tests for the Non-Decreasing and Alternative Hypotheses for the Incomplete Block and Completely Randomized Mixed Design
(North Dakota State University, 2014)This research study proposes a solution to deal with missing observations which is a common problem in real world datasets. A nonparametric approach is used because of its ease of use relative to the parametric approach ... -
Nonparametric Tests for the Umbrella Alternative in a Mixed Design for a Known Peak
(North Dakota State University, 2020)When an assumption from a parametric test cannot be verified, a nonparametric test provides a simple way of conducting a test on populations. The motivation behind conducting a test of the hypothesis is to examine the ... -
On Lasso Estimation of Linear Mixed Model for High Dimensional Longitudinal Data
(North Dakota State University, 2021)With the advancement of technology in data collection, repeated measurements with high dimensional covariates have become increasingly common. The classical statistics approach for modeling the data of this kind is via the ... -
Performance of Permutation Tests Using Simulated Genetic Data
(North Dakota State University, 2022)Disease statuses and biological conditions are known to be greatly impacted by differences in gene expression levels. A common challenge in RNA-seq data analysis is to identify genes whose mean expression levels change ... -
Predicting the Outcomes of NCAA Women’s Sports
(North Dakota State University, 2017)Sports competitions provide excellent opportunities for model building and using basic statistical methodology in an interesting way. More attention has been paid to and more research has been conducted pertaining to men’s ... -
Profile Matching in Observational Studies With Multilevel Data
(North Dakota State University, 2022)Matching is a popular method to use with observational data to replicate desired features of a randomized control trial. A common problem encountered in observational studies is the lack of common support or the limited ... -
Proposed Methods for the Nondecreasing Order-Restricted Alternative in a Mixed Design
(North Dakota State University, 2020)Nonparametric statistics are commonly used in the field of statistics due to their robustness when the underlying assumptions are violated for the usual parametric statistics. In this dissertation, we proposed eight ... -
Proposed Nonparametric Tests for Equality of Location and Scale Against Ordered Alternatives
(North Dakota State University, 2021)Ordered alternatives tests are sometimes used in life-testing experiments and drug-screening studies. An ordered alternative test is sometimes used to gain power if the researcher thinks parameters will be ordered in a ... -
Proposed Nonparametric Tests for the Simple Tree Alternative for Location and Scale Testing
(North Dakota State University, 2020)Location-scale problems arise in many cases, such as, bioinformatics, climate dynamics, finance and medicine (Marozzi, 2013). This research focuses on developing tests to determine whether one or more treatment effects ... -
Proposed Nonparametric Tests for the Simple Tree Alternative in a Mixed Design
(North Dakota State University, 2014)For the general alternative, many test statistics exist for the dependent and independent variables. However, no documented test statistics exist for simple tree alternative for the dependent variables, independent ... -
Proposed Nonparametric Tests for the Simple Tree Alternative in a Mixed Design
(North Dakota State University, 2014)Video summarizing Ph.D. dissertation for a non-specialist audience. -
Proposed Nonparametric Tests for the Umbrella Alternative in a Mixed Design
(North Dakota State University, 2020)Several nonparametric tests are proposed for a mixed design consisting of a randomized complete block design (RCBD) and a completely randomized design (CRD) under the umbrella hypothesis with a known and an unknown peak. ... -
Proposed Nonparametric Tests for the Umbrella Alternative in a Mixed Design for Both Known and Unknown Peak
(North Dakota State University, 2019)In several situations, and among various treatment effects, researchers might test for an umbrella alternative. The need for an umbrella alternative arises in the evaluation of the reaction to drug dosage. For instance, ... -
Proposed Nonparametric Tests for the Umbrella Alternative in a Mixed Design Testing for Location and Location-Scale
(North Dakota State University, 2022)Researchers sometimes use the umbrella alternative when testing for differences in treatment effects, where the parameters increase up to a point and decrease after that point. Sometimes different treatment effects may ... -
A Simulation Study Using a Mixed Model Framework to Analyze the Impact of Sample Size and Variability on Type I Error and Power
(North Dakota State University, 2021)Repeated measures design (or longitudinal study) are commonly seen in many research fields, especially in pharmaceutical clinical trials, agricultural research, and psychology. PROC MIXED (SAS Inc.) is a well-known standard ...