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Differential Modulation of the Structural and Functional Characteristics of Human Matrix Metalloproteinase Isozymes upon Binding to Different Ligands
(North Dakota State University, 2010)
Matrix metalloproteinases (MMPs) are a family of Zn2
+ -dependent, Ca2
+ -containing
endoproteinases involved in tissue remodeling and degradation of the extracellular matrix
(ECM). Human MMP isozymes are known to be ...
Influence of Active Site Ligands and Nanoparticle Surfaces on Human Carbonic Anhydrase Isozymes
(North Dakota State University, 2010)
Carbonic anhydrase (CA) is an ubiquitously distributed zinc containing metallo
enzyme that catalyzes the reversible hydration of carbon dioxide to form bicarbonate and a
proton. Existence of 16 isoenzymes of CA in the ...