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Now showing items 11-20 of 56
Strategic Functionalization of Single Walled Carbon Nanotubes to Manipulate their Electronic and Optical Properties
(North Dakota State University, 2017)
Single-walled carbon nanotubes (SWCNTs) are unique materials that exhibit chirality-specific properties due to their one-dimensional confinement. As a result, they are explored for a wide range of applications including ...
Biophysical Studies of Ligand Binding to Human Histone Deacetylase-8
(North Dakota State University, 2014)
Due to an involvement in various patho-physiological conditions, human histone deacetylases (HDACs) are high priority drug targets for the treatment of several diseases, such as cancer, heart failure, neurodegeneration, ...
Interactions of Light with Organic Chromophores: A Photochemical and Photophysical Investigation
(North Dakota State University, 2018)
Over the past century, light has emerged as a useful tool finding utility in various fields such as device fabrication, the medical field, as well as utility as an energy source. Chemist have adopted this abundant energy ...
Development of Quantitative Lateral Flow Strip Biosensors for the Detection of Cancer Biomarkers
(North Dakota State University, 2019)
The detection of cancer biomarkers is of great importance in oncology. Cancer biomarkers can provide diagnostic information which can aid disease screening and early diagnosis. Further, cancer biomarkers can help predict ...
Effect of Surface Ligands and Surface Defects on the Electronic and Optical Properties of Quantum Dots
(North Dakota State University, 2016)
Quantum dots (QDs) have drawn a special attention since recent past due to their properties such as broad range absorption ability, size tunable narrow emission, high extinction coefficients, and charge carriers ability. ...
Biochemical and Functional Characterization of Rpa2 N-Terminal Phosphorylation during DNA Repair and Checkpoint Adaptation in Saccharomyces Cerevisiae
(North Dakota State University, 2018)
In response to DNA damage, a signaling cascade is activated within cells that promotes cell cycle arrest in order to provide adequate time for DNA repair to occur. Replication Factor A (RFA) is an essential, heterotrimeric ...
Investigating Selected Mechanisms of Modulation of BECN1-mediated Autophagy
(North Dakota State University, 2019)
Autophagy is a lysosomal degradation pathway wherein cytoplasmic components not needed by or harmful to the cell are degraded and recycled. BECN homologs are key autophagy proteins consisting of an intrinsically disordered ...
Late Transition Metal-Catalyst Development for Alkyne Coupling Reactions
(North Dakota State University, 2016)
Alkynes are versatile and valuable synthetic precursors in a variety of organic
transformations and have found tremendous applications in materials science and pharmaceutical
chemistry. In recent years, there has been a ...
Stereospecific Photochemical Transformations Involving Axially Chiral Acrylanilides and a-Oxoamides
(North Dakota State University, 2013)
Asymmetric photochemical transformations have been under-explored due to the ineffectiveness of conventional methodologies/reagents/catalysts (point chiral auxiliaries and inductors) that were generally employed for thermal ...
Surface Chemistry Characterization of Hydrodesulfurization and Methanol Synthesis Model Nanocatalysts
(North Dakota State University, 2012)
Surface science investigations of model catalysts have contributed significantly to heterogeneous catalysis over the past several decades. The unique properties of nanomaterials are being exploited in catalysis for the ...