Browsing Microbiological Sciences by Title
Now showing items 35-54 of 60
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International Infectious Disease Management and its Role in the 'One World, One Health, One Medicine' Concept
(North Dakota State University, 2012)The knowledge that almost 75% of all new human pathogens have animal origins, requires health professionals from all fields, (i.e. human medicine, veterinary medicine, and public health professionals), to work on solving ... -
Investigation of Nutrients as Treatments of Bacterial Biofilms
(North Dakota State University, 2019)Using nutrients bacteria utilize to grow as treatments of bacterial biofilms have been investigated. This dissertation examines the problem of the prevention and treatment of biofilms by: (i) testing the effect of the ... -
Investigations in Asthma Heterogeneity: The Roles of Aspergillus Fumigatus-Derived Eicosanoid Synthases and Occupational Exposures to Grain Dusts on the Development of Fungal Allergic Asthma
(North Dakota State University, 2013)Allergic asthma is an inflammatory syndrome of the respiratory system which changes the airway wall architecture. Using an aeroallergen, murine model of A. fumigatus-mediated asthma, the two studies herein examine the ... -
The Link Between Gut Microbiota Metabolism and Host Gluconeogenesis by Vasoactive Intestinal Peptide
(North Dakota State University, 2022)The gut microbiota (GM) plays a beneficial role in host metabolism. In mammals, the GM ferments dietary fiber into short chain fatty acids (SCFA), like propionate, that improves glucose metabolism. Rats fed a propionate ... -
lntraspecific Variation In Pathogenic Cryptosporidium parvum
(North Dakota State University, 2010)Cryptosporidium causes cryptosporidiosis, an infectious diarrheal disease, which can become chronic and life-threatening in immunocompromised individuals. Cryptosporidium parvum and C. hominis are the primary causes of ... -
Lung Mucosal Response to Repeated Inhalational Insults with Immunomodulatory Agents in a Murine Model of Fungal Asthma: Airway Epithelium Takes the Center Stage
(North Dakota State University, 2013)Asthma is a debilitating disease of the lungs affecting 235 million people worldwide. Fungus-associated asthma leads to a particularly severe type of disease, and exposure to environmental fungi and their products is ... -
The One World / One Health Concept Applied in the Field, Laboratory, and Hospital
(North Dakota State University, 2014)New infectious disease outbreaks demand new approaches for control and prevention of disease. The world’s health organizations have adopted the One World/One Health (OWOH) concept to meet this demand. The previous approach ... -
An Overview of SARS-CoV-2 Covid-19: Epidemiology, Origin, and Pathology
(North Dakota State University, 2020)Following SARS (years 2002-2003) and MERS (year 2012) outbreaks, humans have faced a new highly contagious virus, SARS-COV-2, which began late 2019 and resulted in a pandemic (COVID-19 pandemic). The disease has been spread ... -
Phenotypic and Genomic Assessment of Listeria monocytogenes Virulence
(North Dakota State University, 2019)Listeria monocytogenes is the etiological agent of listeriosis in humans and ruminants causing bacteremia, central nervous system (CNS) infections, abortion, and gastroenteritis among other clinical outcomes. Recent studies ... -
Phenotypic and Genotypic Effects of FlhC Mediated Gene Regulation in Escherichia Coli O157:H7
(North Dakota State University, 2011)Escherichia coli (E.coli) 0157:H7, a pathogen belonging to the enterohemorrhagic group of E.coli, has long been a concern to human health. The pathogen causes a myriad of symptoms in humans, ranging from diarrhea and malaise ... -
Physical and Chemical Treatments for Bacterial Biofilms
(North Dakota State University, 2014)Physical and chemical treatments have been investigated for the treatment to remove biofilms. This thesis examines the problem of the removal and prevention of biofilms by: (i) using a water jet to determine biofilm stability ... -
A Porcine Circovirus Vaccine with Enhanced Capabilities
(North Dakota State University, 2016)Porcine circovirus type 2 (PCV2) is a pathogen of swine. Vaccines against PCV2 are available, although none are capable of differentiating infected from vaccinated animals (DIVA). Positive and negative DIVA markers were ... -
Potential for Phenotypic Plasticity in the Hyperosmotic Stress Response of Diverse E. coli
(North Dakota State University, 2021)Escherichia coli inhabits multiple environments that contain varying physical stresses which emphasize the importance of adaptation. The large pangenome of E. coli can account for some strain-to-strain variances in phenotype, ... -
Preliminary Investigation of Escherichia Coli K12 Biofilm Inhibition on an Antimicrobial Polysiloxane Coating using Whole Transcriptome Profiling
(North Dakota State University, 2012)Whole transcriptome profiling was examined in E. coli K12 when cultured on the surface of a pure polysiloxane coating (Sil) and a polysiloxane coating containing a tethered quaternary ammonium compound (QSil) shown to ... -
Prevalence of Listeria Monocytogenes in the Pre-Harvest Environment: A Landscape Epidemiology Approach
(North Dakota State University, 2016)Listeria monocytogenes is the causative agent of the foodborne disease listeriosis. Although the incidence of listeriosis is lower than that of other foodborne diseases, it’s much higher mortality rate makes it a cause for ... -
Rationally Reconstructed and Attenuated Vaccines for Epidemic Response
(North Dakota State University, 2021)Most of the recent viral outbreaks were caused by highly mutating RNA and single stranded DNA viruses. The availability of safe and effective rapid response vaccines early on in an epidemic situation, along with good vaccine ... -
The Response of Salmonella enterica and Enterohemorrhagic Escherichia coli in Low-Moisture Environments
(North Dakota State University, 2021)The recent increase in outbreaks of low-moisture foods due to contamination with foodborne pathogens has led to an increase in interest of the response of these pathogens to low-moisture environments. In addition, knowledge ... -
Rhomboid Proteases and Surface Adhesins During Cryptosporidium Development
(North Dakota State University, 2013)Cryptosporidium parvum, a primary cause of cryptosporidiosis in humans and livestock worldwide, has a complex life cycle that includes an environmental oocyst stage, and stages of merogony, gametogony, and sporogony that ... -
RNA Viral Prophylaxis: Problems and Potential Solutions
(North Dakota State University, 2019)Over 80% of the newly emerging infectious diseases are caused by RNA viruses. Major global problems associated with the development of vaccines against the RNA virus are their high genetic and antigenic diversity. Hence, ... -
Role of ArcB/ArcA in the Regulation of Biofilm Formation in Escherichia coli in Conjunction with F1hD Expression
(North Dakota State University, 2014)The two goals of this study were to identify the affect that arcB has on biofilm formation and to determine whether this was dependent on AckA. Acetyl phosphate is formed from acetyl-CoA during acetate metabolism and is ...