Genomics & Bioinformatics
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Leveraging Genomics and Transcriptomics for Gene Discovery in Dry Pea
(North Dakota State University, 2024)Over the past two decades, there has been a significant increase in the utilization of DNA marker-based mapping studies to genetically map and further improve complex quantitative traits. A major caveat of this approach ... -
Genome-wide Scan for Loci Affecting Iron Deficieny Chlorosis in Soybean.
(North Dakota State University, 2010)Iron deficiency results in iron deficiency chlorosis (IDC) in soybean grown in the north central regions of the United States. Soybean plants display a variety of symptoms, ranging from slight yellowing of the leaves to ... -
Genomic Analysis of Tan Spot and Stagonospora Nodorum Blotch Resistance in Wheat
(North Dakota State University, 2011)Host-selective toxins, or necrotrophic effectors, are important determinants of disease in both wheat-Stagonospora nodorum and wheat- Pyrenophora tritici-repentis pathosystems. This study describes the identification, ... -
Identification of Stem Rust Resistance Quantitative Trait Loci in Durum Wheat Populations
(North Dakota State University, 2022)Stem rust (Puccinia graminis f. sp. tritici) negatively impacts durum wheat production worldwide. Resistance loci from four resistant landrace durum wheat lines were identified in biparental F¬5¬ recombinant inbred line ... -
Genomic Characterization of Necrotrophic Effector Sensitivity Genes in Wheat
(North Dakota State University, 2022)The necrotrophic fungal pathogens Parastagonospora nodorum and Pyrenophora tritici-repentis cause the diseases septoria nodorum blotch (SNB) and tan spot, respectively, reducing yield by decreasing the photosynthetic area ... -
The Genomic Alteration Landscape of Pancreatic Duct Adenocarcinoma
(North Dakota State University, 2022)By 2030, PDAC is projected to be the second leading cause of cancer-related death in the US. PDAC is a multifactorial disease driven by genomic alterations. Understanding this alteration landscape will both refine the ... -
Mapping and Characterization of Yield Component Traits and Septoria Nodorum Blotch Susceptibility in Wheat
(North Dakota State University, 2021)Wheat, a major global economic crop and food source, is currently threatened by climate change and the cascading effects, including increased disease pressure. Additionally, wheat yields have not increased significantly ... -
Validation of the Pyrenophora teres f. teres PttBee1 Region and Mapping of Resistance to P. teres f. maculata in Durum
(North Dakota State University, 2021)Pyrenophora teres is a fungal pathogen of barley and other closely related grass species. Two forms of the pathogen, P. teres f. teres and P. teres f. maculata, are the causative agents of net form net blotch and spot form ... -
Bioinformatic Analysis to Identify and Understand Aberrant DNA Methylation Pattern Associated with Pancreatic Cancer
(North Dakota State University, 2021)In this study, we searched for significant hypo and hyper methylation CpG (5'-C-phosphate-G-3') probes from The Cancer Genome Atlas (TCGA) datasets. First, the relationship between hypo and hypermethylation pattern in ... -
Using Machine Learning and Text Mining Algorithms to Facilitate Research Discovery of Plant Food Metabolomics and Its Application for Human Health Benefit Targets
(North Dakota State University, 2020)With the increase in scholarly articles published every day, the need for an automated systematic exploratory literature review tool is rising. With the advance in Text Mining and Machine Learning methods, such data ... -
Mapping Ur-6, a Bean Rust Resistance Gene in Common Bean
(North Dakota State University, 2020)Bean rust, caused by the fungus Uromyces appendiculatus (Pers.:Pers) Unger, is a disease of common bean (Phaseolus vulgaris) prevalent in the Americas and Africa. The most cost-effective countermeasure to bean rust is ... -
Genomic Analysis of Septoria nodorum Blotch Susceptibility Genes Snn1 and Snn2 in Wheat
(North Dakota State University, 2019)Septoria nodorum blotch is a disease of wheat caused by the necrotrophic fungus Parastagonospora nodorum. In the wheat-P. nodorum pathosystem, recognition of pathogen-produced necrotrophic effectors (NEs) by dominant host ... -
Comparative Analysis of Zinc Oxide Nanoparticles Induced Transcriptomic Responses in Arabidopsis
(North Dakota State University, 2019)The impact that zinc oxide nanoparticles (ZnONP) have on plant physiological responses was evaluated by comparing gene expression changes after Arabidopsis thaliana plants were exposed to ZnONP, in comparison with ionic ... -
Variation in Core and Accessory Parts of Genome of Escherichia Coli Isolated from Soil from Riparian Areas in New York State
(North Dakota State University, 2016)Escherichia coli is commensal bacteria and is a symbiont of the digestive system of vertebrates. Due to frequent deposition of E. coli into extrahost habitats (soil, water), approximately half of its population exists as ... -
Genomic Analysis of Domestication-Related Traits and Stem Rust Resistance in Tetraploid Wheat
(North Dakota State University, 2017)Modern durum and common wheat cultivars were developed from ancient wheat ancestors by natural and artificial selection of agronomic and domestication traits, which ultimatey decreased their genetic diversity and made them ... -
Genetic Characterization of Dormancy in Durum Wheat
(North Dakota State University, 2012)Two populations derived by crossing LDN x LDN Dic-3A (Population I) and LDN x LDN Dic-3B (Population II) were genetically characterized for the seed dormancy present on chromosome 3A and 3B of durum wheat. The genes for ... -
Genome-Wide Association Mapping of Host Resistance to Stem Rust, Leaf Rust, Tan Spot, and Septoria Nodorum Blotch in Cultivated Emmer Wheat
(North Dakota State University, 2015)Cultivated emmer wheat (Triticum turgidum ssp. dicoccum) is a good source of genes for resistance to several major diseases of wheat. The objectives of this study were to use genome-wide association analysis to detect ... -
Unraveling the Genetic Architecture of Agronomic Traits and Developing a Genome Wide InDel Panel in Common Bean (Phaseolus vulgaris)
(North Dakota State University, 2015)Common bean (Phaseolus vulgaris) is an economically important legume. The agronomic characteristics of this crop such as days to flower, growth habit and seed yield affect breeding strategies. However, little is known about ...