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Design and Evaluation of Two Hybrid Genome Assembly Approaches Using Illumina, Roche 454, and PacBio Datasets
(North Dakota State University, 2016)
The assembly of next-generation sequencing reads is one of the most challenging and important tasks in bioinformatics. There are many different types of assembly algorithms and programs that have been developed to assemble ...
Disease Similarity Using Biological Module Dysregulation Profile
(North Dakota State University, 2016)
Diseases can be grouped according to phenotypic and genotypic similarities. Gene expression and micro-RNA data paved the way to look inside the genetic coding and classify diseases accurately. Modern system biology seeks ...