Certified athletic trainers (ATs) are often tasked to treat Medial Tibial Stress Syndrome (MTSS) in the athletic population. Further, they are expected to provide effective treatment approaches based on the scientific evidence. The goal of this study was to review current treatment options chosen by ATs and to assess possible relationships between AT’s demographics and their chosen treatment options. This web-based survey was completed by 131 ATs. The survey collected demographic information and treatment options used. Data were analyzed to assess the relationships between treatment options and independent variables including clinical setting, education, and years of experience. Four relationships were found between independent variables and the use of treatment options. Based on a review of the literature, most treatment options selected by ATs are supported by existing evidence. It is essential for ATs to have knowledge of the best treatment option based on available resources in their particular clinical setting.