This thesis studies the question of how the quality of the built environment affects all aspects of well-being in its users. The topic will be explored through mixed method research with an emphasis on the relationships between human well-being and the built environment, with additional focus on the quality of design relating to architectural tectonics. The building typology used to delve into this question is a cancer treatment center located in Blue Earth, Minnesota. The treatment center will be operated as a satellite of the United Hospital District, and will seek to have architecturally positive impacts on the people who interact with the building, including patients and doctors, as well as other staff and visitors.