The primary objective of this thesis is to explore how an understanding of neuroscience can influence the human perception of the built environment. Advancement in the field of neuroscience has allowed for a greater understanding of how we perceive the world at a neurological level. An effort to understand our experience of the built environment has been theorized since the time of Vitruvius. This thesis investigates these relationships through an urban in-fill project in downtown Fargo, North Dakota.