Browsing Larry (Lawrence) Reynolds - Thesis Committee by Title
Now showing items 11-23 of 23
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Identification and Characterization of Binding Target Proteins of Cancer Stem Cell Inhibitor Salinomycin in Human Neuroblastoma
(North Dakota State University, 2015)Salinomycin, a widely used anti-coccidial agent, was recently identified as a cancer stem cell (CSC) inhibitor from a library of 16,000 natural and commercial chemical compounds based on its highly selective inhibitory ... -
The Impact of Digestive Enzymes in the Ruminant Animal
(North Dakota State University, 2016)Understanding the enzymatic activity in ruminant digestive systems is essential for securing adequate growth, reproduction and overall metabolism. In order to evaluate the impact of various nutritional sources and dietary ... -
Impacts of Beef Cow Nutrition on Conceptus Development
(North Dakota State University, 2013)Two experiments were conducted to determine the effect of maternal nutrient restriction followed by realimentation during early to mid-gestation on uterine blood flow (BF), maternal performance, and conceptus development ... -
Impacts of Supplemental Arginine on Ewe Reproductive Performance
(North Dakota State University, 2014)The objective of this study was to determine the effects of injectable and oral arginine (Arg) supplementation provided 14 d post-breeding on reproductive performance of fall lambing ewes. Upon estrus detection (d 0) ewes ... -
Implementation of Fourier Repetitive Control in Labview
(North Dakota State University, 2014)This thesis presents position control as well as current (torque) control of a DC servo motor with a periodic input. Position control is achieved by using Fourier repetitive control scheme. Simulation on position control ... -
Influence of Maternal Nutrient Intake on Placental Vascular Function in Pregnant Beef Cows
(North Dakota State University, 2014)We hypothesized that global maternal nutrient restriction during early and mid-gestation followed by realimentation in pregnant beef cows would alter placental arterial vascular function. We tested changes in placental ... -
An Insilico Design of Nanoclay Based Nanocomposites and Scaffolds In Bone Tissue Engineering
(North Dakota State University, 2016)A multiscale in silico approach to design polymer nanocomposites and scaffolds for bone tissue engineering applications is described in this study. This study focuses on the role of biomaterials design and selection, ... -
Ligand Binding and Catalysis in Selected Sirtuin Isozymes
(North Dakota State University, 2016)Due to their intimate roles in survival, longevity as well as pathogenesis via “epigenetic” and “metabolic” regulatory mechanisms, sirtuins have gained considerable interest toward undertaking detailed biochemical/biophysical ... -
Maternal Nutritional Plane and Endogenous Retroviral Gene Elements, Pregnancy Hormones, and Placental Vascularity and Angiogenic Factors during the Establishment of Pregnancy in Beef Cattle
(North Dakota State University, 2016)In order to meet the projected food demands by 2050, animal agriculture must increase production of animal products on the same or decreased land area through increased efficiency. Early gestation is one area to increase ... -
Quantifying Seasonal Variation in Physiological Condition of Adult Franklin's Gull (Luecophaeus Pipixcan) during Nesting
(North Dakota State University, 2011)Understanding seasonal variation in adult physiological condition is important for developing hypotheses on how nest initiation, adult condition, chick development and recruitment are related in Franklin's gull and other ... -
The Role of Platelet-Derived Growth Factor Receptor Signaling in Medulloblastoma Metastasis
(North Dakota State University, 2013)Medulloblastoma is the most common brain tumor in children and one third of the patients remain incurable. Tumor metastasis is one of the primary reasons for its high mortality rate. Despite evidence of overexpression of ... -
Structural Studies of BECN1, A Key Autophagy Protein, and Intrinsically Disordered Regions in Autophagy Proteins
(North Dakota State University, 2016)Autophagy, a conserved catabolic process required for cellular homeostasis in eukaryotes, is regulated by many proteins. The central goal of my doctoral research is to investigate conformational flexibility of autophagy ... -
Towards Identifying the Physical and Molecular Components Involved in Resistance to Leaf Rust Pathogen Puccinia Triticina in Wheat and Barley
(North Dakota State University, 2016)Genetic resistance is the preferred method to reduce yield losses caused by many diseases including wheat leaf rust. However, in many cases host resistance seems to be short-lived. For decades, scientists have tried and ...