Search
Now showing items 1-10 of 72
Stereoselective Carbon-Carbon Bond Construction Using Indium and Bismuth: New Methods in Green Chemistry
(North Dakota State University, 2012)
Selective chemical reactions that can be accomplished with minimal waste using non-toxic catalysts and reagents will allow for new greener chemical processes for future environmentally sustainable technologies. This work ...
Synthesis, Photophysics, Reverse Saturable Absorption, and Photodynamic Therapy of Iridium(III) Complexes Bearing Different Degrees of p-conjugation on the Ligands
(North Dakota State University, 2019)
Octahedral d6 iridium(III) complexes possess rich photophysical properties. The most distinct phtotphysical properties of the Ir(III) complexes are their high triplet excited-state formation quantum yields, long-lived ...
Structural Basis for the Regulation of a Conserved TonB-dependent Iron Transport System via Cell-surface Signaling in Gram-negative Bacteria
(North Dakota State University, 2017)
Cell-surface signaling (CSS) pathways are highly conserved systems in Gram-negative bacteria that allow the cell to efficiently respond to environmental stimuli through transcriptional regulation. Three distinct proteins ...
Atropisomeric Chromophores as Catalysts and Substrates for Asymmetric Light Induced Transformations
(North Dakota State University, 2016)
Photochemical transformations hold a unique place as they can provide access to molecules with unique stereochemical and structurally complex scaffolds, thus serving as a complementary approach to thermal transformations. ...
4-Dimethylamino Pyridine (DMAP) Catalyst with Fluxional Chirality: Synthesis and Applications
(North Dakota State University, 2016)
Organocatalysis using small organic molecules to catalyze organic transformations, has
emerged as a powerful synthetic tool that is complementary to metal-catalyzed transformations
and remarkably promote stereoselective ...
Biological Effects of Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase Activating Polypeptide Receptor 1 (VPAC1) and VPAC2 on Chemotaxis and its Regulation of the Tumor Suppressor Ikaros in Leukemic T Cells
(North Dakota State University, 2012)
One in three children diagnosed with cancer has leukemia. Leukemia patients with mutations in the tumor suppressor transcription factor Ikaros (IK), an anti-leukemic factor that is critical for the development of blood ...
Attempted Total Syntheses of a Novel Lycopodine-Class Alkaloid and (R)-Myricanol, Compounds for the Treatment of Alzheimer's Disease
(North Dakota State University, 2013)
Alzheimer's Disease (AD) is a significant challenge to both the pharmaceutical world as well as the synthetic organic chemistry world. One of the most important problems in this field is the lack of a unified approach to ...
Adsorption Kinetics and Dynamics of Small Molecules on Graphene and Graphene oxide
(North Dakota State University, 2018)
Graphene is an allotrope of carbon composed of sp2 hybridized carbon and arranged into a honeycomb lattice. Graphene is a mechanically strong material (200 times stronger than steel) and has high carrier mobility, high ...
Novel Synthetic Routes to Complex Amines: the Catalytic Hydroamination of Alkynes and Hydroimination of Allenes
(North Dakota State University, 2016)
Amines are valuable targets for synthesis in contexts of both research and industrial applications. This work proposes two atom-economical methods—hydroamination (HAM) and hydroimination (HIM)—as C-N bond formation strategies. ...
Carbon Nanotubes-Based Lateral Flow Biosensor for Sensitive and Rapid Detection of DNA Sequence
(North Dakota State University, 2017)
Sensitive detection for DNA has drawn great attention in plenty of different areas such as genetics therapy and basic discovery research. Recently, nucleic acid lateral flow biosensor (NALFB) has gained considerable attention ...