Browsing Chemistry & Biochemistry Masters Theses by Title
Now showing items 1-19 of 19
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Applications of Dithieno [3,2-B2',3'-D] Pyrroles and its Analogues to Conjugated Materials
(North Dakota State University, 2014)The promise of semiconducting materials with tunable electronic and optical properties that share the same mechanical flexibility, low production costs and ease of processing displayed by traditional polymers fuels the ... -
Carbon Nanotubes-Based Lateral Flow Biosensor for Sensitive and Rapid Detection of DNA Sequence
(North Dakota State University, 2017)Sensitive detection for DNA has drawn great attention in plenty of different areas such as genetics therapy and basic discovery research. Recently, nucleic acid lateral flow biosensor (NALFB) has gained considerable attention ... -
Characterizing the Roles of Exit Tunnel Residues in Ligand Binding and Catalysis of Histone Deacetylase-8
(North Dakota State University, 2014)Histone deacetylases are an important class of enzymes that catalyze the hydrolysis of acetyl-L-lysine side chains in histone and non-histone proteins to yield L-lysine and acetate, effecting the epigenetic regulation of ... -
Developing Platform Chemicals from Renewable Resources
(North Dakota State University, 2013)The Department of Energy has listed 5-hydroxymethylfurfural (HMF) and 2,5-furandicarboxylic acid (FDCA) as two of the twelve building blocks derived from cellulosic biomass. HMF can serve as a renewable platform for the ... -
The Development and Use of Chiral 4-Dimethylaminopyridine-N-Oxide as an Organocatalyst
(North Dakota State University, 2018)Organocatalysis is a field that has bloomed over the last decades. With the field’s promise of being able to mimic nature and afford products in a synergistic manner to traditional Lewis acid catalysis, several interesting ... -
Diastereoselective Conjugate Radical Additions to ~-Pyrones
(North Dakota State University, 2009)A convenient protocol for functionalization of ~-pyrones has been developed. Conjugate radical addition and tandem addition-trapping protocols allowed accessing highly substituted pyrones in a single operation with high ... -
Identification of Aptamer Specific for Carcinoembryonic Antigen and its Analytical Applications
(North Dakota State University, 2017)Carcinoembryonic Antigen (CEA) is an approved cancer biomarker by the Food and Drug Administration (FDA) for the early detection, diagnosis, and for the use in the regular screening of patients at high risk for the development ... -
Identification of Novel RPA-Protein Interactions Using the Yeast Two Hybrid Assay and Identification of Regions Important for Interaction Between RPA and Rad24
(North Dakota State University, 2013)Replication Protein A (RPA) [Replication Factor A (RFA) in yeast] is an ssDNA binding protein composed of Rpa1, Rpa2, and Rpa3 and involved in numerous DNA processing pathways such as Replication, Recombination, and Repair. ... -
Infrared Diode Laser Spectroscopic Study of Combustion Related Kinetics
(North Dakota State University, 2016)In the introduction section background into the subject of combustion chemistry is presented. The topics included are combustion mechanisms, combustion pollutants, and infrared absorption spectroscopy. Chapter two describes ... -
Interactions of Synthetic Metal Porphyrinates with PhuS, a Cytoplasmic Heme Trafficking Protein from Pseudomonas aeruginosa
(North Dakota State University, 2010)Pseudomonas aeruginosa is an opportunistic, Gram negative, bacterial pathogen that commonly establishes infection in immunocompromised individuals. It contains protein-based, iron uptake pathways that target both heme ... -
A Metal Catalyzed Approach for Heterocycle Coupling Reactions
(North Dakota State University, 2021)Heterocycles are cyclic compounds which contain atoms from at least two different elements. The work in this thesis describes methods we developed for the direct chemical transformation of indole heterocycles with various ... -
Novel Synthetic Routes to Complex Amines: the Catalytic Hydroamination of Alkynes and Hydroimination of Allenes
(North Dakota State University, 2016)Amines are valuable targets for synthesis in contexts of both research and industrial applications. This work proposes two atom-economical methods—hydroamination (HAM) and hydroimination (HIM)—as C-N bond formation strategies. ... -
Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling Reaction of Aromatic Esters and Aromatic Diesters with Arylboronic Acids
(North Dakota State University, 2020)The palladium-catalyzed cross-coupling reactions for the functionalization of the ester bond provides a significant overall improvement in the catalytic system as compared to aryl halides/pseudo-halides electrophilic ... -
Regioselective and Enantioselective Nitrone Cycloadditions to Alkynones.
(North Dakota State University, 2010)There has been a need in agriculture, medicine, and organic chemistry for enantiopure isoxazolines. A direct method for their synthesis is from the cycloaddition of 1,3-dipoles and alkynes. Alkynones are difficult ... -
Supramolecular Functionalization of Single-Walled Carbon Nanotubes
(North Dakota State University, 2013)Single-walled carbon nanotubes (SWNTs) possess extraordinary mechanical strength, thermal and electrical conductivity. These properties make them very attractive in many applications in the fields of nanotechnology, ... -
Synthesis and Applications of Dialdehydes
(North Dakota State University, 2018)Due to their reactivity and ease of functional group interconversions, aldehydes have wide-ranging applications in polymer synthesis, such as polyacetals, epoxy resins, and polyurethanes. Recently, room temperature synthesis ... -
Synthesis and Photophysics of Platinum(II) Terdentate and Bidentate Complexes.
(North Dakota State University, 2010)Platinum(ll) terdentate and bidentate complexes possess square-planar d8 configuration. The moderate metal-to-ligand charge-transfer (1MLCT) absorption, 3MLCT emission, and broadband excited-state absorption are the ... -
Synthesis of Precursors to Non-isocyanate Polyurethanes
(North Dakota State University, 2018)Biobased diamines are excellent precursors for the synthesis of non-isocyanate polyurethanes (NIPUs). We have prepared several biobased diamines using three different reactions for their synthesis. In the first method, we ... -
VIP Induces Snail1, A Master EMT Regulator: Upregulation in A375 Cancer Cells
(North Dakota State University, 2021)VIP is neurotransmitter with pleiotropic functions in mammals. It is expressed by a large number of tissues, including the CNS, PNS, innate and adaptive immune systems. VIP has two endogenous G-protein coupled receptors, ...