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Characterizing the Roles of Exit Tunnel Residues in Ligand Binding and Catalysis of Histone Deacetylase-8
(North Dakota State University, 2014)
Histone deacetylases are an important class of enzymes that catalyze the hydrolysis of acetyl-L-lysine side chains in histone and non-histone proteins to yield L-lysine and acetate, effecting the epigenetic regulation of ...