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Transmission and Pathogenesis of Swine Torque-Teno Virus 1 (TTSuV1)
(North Dakota State University, 2019)
Torque-teno viruses (TTVs) are small ubiquitous non-enveloped single-stranded circular DNA viruses. Since their discovery in a post-transfusion hepatitis patient, they have been isolated in several vertebrate hosts with ...
Investigation of Nutrients as Treatments of Bacterial Biofilms
(North Dakota State University, 2019)
Using nutrients bacteria utilize to grow as treatments of bacterial biofilms have been investigated. This dissertation examines the problem of the prevention and treatment of biofilms by: (i) testing the effect of the ...
RNA Viral Prophylaxis: Problems and Potential Solutions
(North Dakota State University, 2019)
Over 80% of the newly emerging infectious diseases are caused by RNA viruses. Major global problems associated with the development of vaccines against the RNA virus are their high genetic and antigenic diversity. Hence, ...
Heterogeneity in Phenotypic Response of Foodborne Pathogens to Control Measures
(North Dakota State University, 2019)
Foodborne pathogens are estimated to cause 48 million foodborne illnesses through consumption of contaminated food annually. Designing efficient control measures is vital to reducing foodborne illnesses. The modern trend ...
Interactions of Aspergillus fumigatus and Pseudomonas aeruginosa Contribute to Respiratory Disease Severity and Death
(North Dakota State University, 2019)
The lung was recently identified to consist of a complex microenvironment made up of microorganisms that interact with one another and the host cells via direct and indirect interactions. As a result, understanding the ...
Phenotypic and Genomic Assessment of Listeria monocytogenes Virulence
(North Dakota State University, 2019)
Listeria monocytogenes is the etiological agent of listeriosis in humans and ruminants causing bacteremia, central nervous system (CNS) infections, abortion, and gastroenteritis among other clinical outcomes. Recent studies ...
Characterizing the Impact of Stress Exposure on Survival of Foodborne Pathogens
(North Dakota State University, 2019)
Bacterial pathogens transmitted by the fecal-oral route endure several stresses during survival/growth in host and non-host environments. For foodborne pathogens, understanding the range of phenotypic responses to stressors ...