Search
Now showing items 1-10 of 16
Transmission and Pathogenesis of Swine Torque-Teno Virus 1 (TTSuV1)
(North Dakota State University, 2019)
Torque-teno viruses (TTVs) are small ubiquitous non-enveloped single-stranded circular DNA viruses. Since their discovery in a post-transfusion hepatitis patient, they have been isolated in several vertebrate hosts with ...
The Effects of Agricultural Factors on Foodborne Bacterial Pathogen Isolation, Attachment, and Survival
(North Dakota State University, 2020)
The pathogens enterohemorrhagic Escherichia coli (EHEC), Salmonella enterica, and Listeria monocytogenes are prominent causes of foodborne illness. If they reach the pre- or post-harvest environment of produce, they can ...
Investigation of Nutrients as Treatments of Bacterial Biofilms
(North Dakota State University, 2019)
Using nutrients bacteria utilize to grow as treatments of bacterial biofilms have been investigated. This dissertation examines the problem of the prevention and treatment of biofilms by: (i) testing the effect of the ...
RNA Viral Prophylaxis: Problems and Potential Solutions
(North Dakota State University, 2019)
Over 80% of the newly emerging infectious diseases are caused by RNA viruses. Major global problems associated with the development of vaccines against the RNA virus are their high genetic and antigenic diversity. Hence, ...
Rhomboid Proteases and Surface Adhesins During Cryptosporidium Development
(North Dakota State University, 2013)
Cryptosporidium parvum, a primary cause of cryptosporidiosis in humans and livestock
worldwide, has a complex life cycle that includes an environmental oocyst stage, and stages of
merogony, gametogony, and sporogony that ...
Lung Mucosal Response to Repeated Inhalational Insults with Immunomodulatory Agents in a Murine Model of Fungal Asthma: Airway Epithelium Takes the Center Stage
(North Dakota State University, 2013)
Asthma is a debilitating disease of the lungs affecting 235 million people worldwide. Fungus-associated asthma leads to a particularly severe type of disease, and exposure to environmental fungi and their products is ...
Phenotypic and Genotypic Effects of FlhC Mediated Gene Regulation in Escherichia Coli O157:H7
(North Dakota State University, 2011)
Escherichia coli (E.coli) 0157:H7, a pathogen belonging to the enterohemorrhagic group of E.coli, has long been a concern to human health. The pathogen causes a myriad of symptoms in humans, ranging from diarrhea and malaise ...
Genetic Disruption of VIP Signaling Alters Intestinal Microbial Structure and Immunity
(North Dakota State University, 2018)
Vasoactive intestinal peptide (VIP) regulates clock gene expression in the brain that synchronizes diurnal feeding behaviors in mammals. In the gastrointestinal (GI) tissues, VIP influences host nutrient absorption from ...
Glycan Triggers of Life Cycle Development in the Apicomplexan Parasite Cryptosporidium
(North Dakota State University, 2017)
Cryptosporidium is an apicomplexan parasite that causes the diarrheal disease cryptosporidiosis, an infection that can become chronic and life threating in immunocompromised and malnourished individuals. Development of ...
Heterogeneity in Phenotypic Response of Foodborne Pathogens to Control Measures
(North Dakota State University, 2019)
Foodborne pathogens are estimated to cause 48 million foodborne illnesses through consumption of contaminated food annually. Designing efficient control measures is vital to reducing foodborne illnesses. The modern trend ...