Materials & Nanotechnology Doctoral Work: Recent submissions
Now showing items 1-20 of 28
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Dynamic 3D In Vitro Bone Metastatic Testbeds for Prostate and Breast Cancer
(North Dakota State University, 2022)Metastatic prostate cancer spreads preferentially to the bone, causing skeletal complications associated with significant morbidity and a poor prognosis, despite current therapeutic approaches. Increasing evidence suggests ... -
Study of New Functionalized Nanomaterials for Non-Invasive Point-of-Care Biosensor Devices
(North Dakota State University, 2021)Early disease detection and in-time health monitoring via novel sensing systems is highly demanded for modern medicine and health management. Recent development in nanotechnology and nanomaterials such as functionalized ... -
In-Silico Investigation of Geological and Biological Materials by Molecular Dynamics Simulations
(North Dakota State University, 2021)Molecular dynamics (MD) simulation is a computational technique that predicts the time-dependent behavior of a molecular system utilizing molecular mechanics. MD simulations are extensively employed in the scientific arena ... -
Enhanced Bone Tissue Regeneration Enabled with Tissue-Engineered Interlocking Nanoclay Scaffolds and Bone Morphogenic Proteins
(North Dakota State University, 2022)About 6 million bone fractures occur annually in the US; 30% require bone grafting transplants to aid bone healing. Well-established clinical therapy techniques for bone regeneration suffer from limited availability, higher ... -
Manipulation and Isolation of Biomolecules Using Dielectrophoretic and Hydrodynamic Methods
(North Dakota State University, 2021)Novel particle manipulation techniques are developed to separate, isolate, and control a wide range biomolecules from DNA to cells in complex solution such as whole blood. First, we show that integrating an insulating tip ... -
Adhesion With Slender Structures: Tape Loops, Crumples, and Origami
(North Dakota State University, 2021)The desire for improved adhesive systems led us to examine three geometries: tape loops, crumples, and origami shapes. The tape loop is mechanically interesting because it is stable in more than one configuration. For ... -
Lead Halide Perovskite Nanocrystals: Photophysical and Photochemical Dynamics
(North Dakota State University, 2021)Lead halide perovskites nanocrystals (LHP NCs) are a recent novel material of ‘high-defect tolerance’ that has been synthesized which have provided a new platform for opto-electronic devices, such as photovoltaics and ... -
Tissue-Engineered Nanoclay-Based Bone-Mimetic 3D In Vitro Testbed for Studying Breast Cancer Metastasis to Bone
(North Dakota State University, 2020)Breast cancer shows a high affinity towards the bone, causing bone-related complications leading to poor clinical prognosis. Approximately 80% of breast cancer patients die within five years after primary cancer has ... -
Non-Thermal Plasma Synthesis of Luminescent Silicon Nanocrystals from Cylclohexasilane
(North Dakota State University, 2019)In this report we establish cyclohexasilane (CHS) as a reliable precursor for non-thermal plasma synthesis of high quality photoluminescent silicon nanocrystals (SiNCs). We demonstrate that this synthesis approach can ... -
Flexible Nanocomposite Thin Films for Electronic Devices
(North Dakota State University, 2019)Electronic technology is moving towards flexible, durable, and smaller devices with multifunctional capability. To accelerate this movement, creating materials with outstanding properties is critical. Nanocomposites based ... -
Evaluating Mechanisms of Metastasis of Prostate Cancer to Bone Using 3D Bone-Mimetic Tissue Engineered Scaffolds
(North Dakota State University, 2018)The complex nature of cancer metastasis necessitates the development of a cancer model based on specific metastatic stages. In this dissertation, we report a polymer-nanoclay based in vitro tumor model which recapitulates ... -
Lattice Gases with Molecular Dynamics Collision Operator
(North Dakota State University, 2018)The purpose of this dissertation is to provide a direct microscopic underpinning for lattice Boltzmann (and lattice gas) methods. Lattice gases are idealized discrete models that conserve mass and momentum. These conservation ... -
An Electron Energy-Loss Spectroscopic Investigation of Molecular Interactions at Hydroxyapatite-Collagen Interfaces in Healthy and Diseased (Osteogenesis Imperfecta) Human Bone and Biomineralized Tissue-Engineered Bone
(North Dakota State University, 2018)At its primary level (nm scale) bone is a nanocomposite consisting of a mineral (hydroxyapatite) phase which gives bone its strength and an organic (type I collagen) phase giving bone its fracture toughness. Hydroxyapatite, ... -
Silicon Nanocrystals: Optical Properties and Self Assembly
(North Dakota State University, 2018)Silicon nanocrystal’s (SiNCs) size dependent optical properties and nontoxic nature portend potential applications across a broad range of industries. With any of these applications, a thorough understanding of SiNC ... -
Synthesis, Characterization, and Modeling of New Molecule-Based Magnets
(North Dakota State University, 2015)The chemical bond and its role as a mediator of magnetic exchange interaction remains an important aspect in the study of magnetic insulators and semiconductors. The M[TCNE] (M = transition metal, TCNE = tetracyanoethylene) ... -
Experimental Evaluation of Multiscale Behavior of Human Bone
(North Dakota State University, 2014)Bone is the most important structural member of the human body. It has a unique hierarchical structure and its primary constituents, collagen molecules and hydroxyapatite, are arranged in a staggered pattern at nanometer ... -
Optical Properties and Ensemble Characteristics of Size Purified Silicon Nanocrystals
(North Dakota State University, 2014)Nanotechnology is at the forefront of current scienti c research and nanocrystals are being hailed as the `arti cial' atoms of the 21st century. Semiconducting silicon nanocrystals (SiNCs) are prime candidates for potential ... -
Laser-Assisted Advanced Assembly for MEMS Fabrication
(North Dakota State University, 2014)Micro Electro-Mechanical Systems (MEMS) are currently fabricated using methods originally designed for manufacturing semiconductor devices, using minimum if any assembly at all. The inherited limitations of this approach ... -
Biomimetic Nanoclay Scaffolds for Bone Tissue Engineering
(North Dakota State University, 2014)Tissue engineering offers a significant potential alternative to conventional methods for rectifying tissue defects by evoking natural regeneration process via interactions between cells and 3D porous scaffolds. Imparting ... -
Multicomponent Doped Barium Strontium Titanate Thin Films for Tunable Microwave Applications
(North Dakota State University, 2014)In recent years there has been enormous progress in the development of barium strontium titanate (BST) films for tunable microwave applications. However, the properties of BST films still remain inferior compared to bulk ...