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Bioinformatic Analysis to Identify and Understand Aberrant DNA Methylation Pattern Associated with Pancreatic Cancer
(North Dakota State University, 2021)
In this study, we searched for significant hypo and hyper methylation CpG (5'-C-phosphate-G-3') probes from The Cancer Genome Atlas (TCGA) datasets. First, the relationship between hypo and hypermethylation pattern in ...
Mapping Ur-6, a Bean Rust Resistance Gene in Common Bean
(North Dakota State University, 2020)
Bean rust, caused by the fungus Uromyces appendiculatus (Pers.:Pers) Unger, is a disease of common bean (Phaseolus vulgaris) prevalent in the Americas and Africa. The most cost-effective countermeasure to bean rust is ...
Validation of the Pyrenophora teres f. teres PttBee1 Region and Mapping of Resistance to P. teres f. maculata in Durum
(North Dakota State University, 2021)
Pyrenophora teres is a fungal pathogen of barley and other closely related grass species. Two forms of the pathogen, P. teres f. teres and P. teres f. maculata, are the causative agents of net form net blotch and spot form ...
Mapping and Characterization of Yield Component Traits and Septoria Nodorum Blotch Susceptibility in Wheat
(North Dakota State University, 2021)
Wheat, a major global economic crop and food source, is currently threatened by climate change and the cascading effects, including increased disease pressure. Additionally, wheat yields have not increased significantly ...
Using Machine Learning and Text Mining Algorithms to Facilitate Research Discovery of Plant Food Metabolomics and Its Application for Human Health Benefit Targets
(North Dakota State University, 2020)
With the increase in scholarly articles published every day, the need for an automated systematic exploratory literature review tool is rising. With the advance in Text Mining and Machine Learning methods, such data ...
The Genomic Alteration Landscape of Pancreatic Duct Adenocarcinoma
(North Dakota State University, 2022)
By 2030, PDAC is projected to be the second leading cause of cancer-related death in the US. PDAC is a multifactorial disease driven by genomic alterations. Understanding this alteration landscape will both refine the ...
Genomic Characterization of Necrotrophic Effector Sensitivity Genes in Wheat
(North Dakota State University, 2022)
The necrotrophic fungal pathogens Parastagonospora nodorum and Pyrenophora tritici-repentis cause the diseases septoria nodorum blotch (SNB) and tan spot, respectively, reducing yield by decreasing the photosynthetic area ...
Identification of Stem Rust Resistance Quantitative Trait Loci in Durum Wheat Populations
(North Dakota State University, 2022)
Stem rust (Puccinia graminis f. sp. tritici) negatively impacts durum wheat production worldwide. Resistance loci from four resistant landrace durum wheat lines were identified in biparental F¬5¬ recombinant inbred line ...