Browsing Cellular & Molecular Biology Doctoral Work by Title
Now showing items 14-17 of 17
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Regulation of Insulin- and Insulin Receptor-Encoding mRNAS in Rainbow Trout, Oncorhynchus Mykiss
(North Dakota State University, 2012)In this work, rainbow trout were used as a model system to examine the regulation of insulin (INS)- and insulin receptor (IR)-encoding mRNA expression profiles. INS- and IR-encoding mRNAs were isolated, cloned, and sequenced; ... -
The Role of Platelet-Derived Growth Factor Receptor Signaling in Medulloblastoma Metastasis
(North Dakota State University, 2013)Medulloblastoma is the most common brain tumor in children and one third of the patients remain incurable. Tumor metastasis is one of the primary reasons for its high mortality rate. Despite evidence of overexpression of ... -
Structural Studies of BECN1, A Key Autophagy Protein, and Intrinsically Disordered Regions in Autophagy Proteins
(North Dakota State University, 2016)Autophagy, a conserved catabolic process required for cellular homeostasis in eukaryotes, is regulated by many proteins. The central goal of my doctoral research is to investigate conformational flexibility of autophagy ... -
Therapeutic Potential of Piperlongumine for Pancreatic Ductal Adenocarcinoma
(North Dakota State University, 2019)Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal malignancies because it is often diagnosed at a late disease stage and has a poor response rate to currently available treatments. Therefore, it is critical ...