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Now showing items 21-30 of 72
Late Transition Metal-Catalyst Development for Alkyne Coupling Reactions
(North Dakota State University, 2016)
Alkynes are versatile and valuable synthetic precursors in a variety of organic
transformations and have found tremendous applications in materials science and pharmaceutical
chemistry. In recent years, there has been a ...
Stereospecific Photochemical Transformations Involving Axially Chiral Acrylanilides and a-Oxoamides
(North Dakota State University, 2013)
Asymmetric photochemical transformations have been under-explored due to the ineffectiveness of conventional methodologies/reagents/catalysts (point chiral auxiliaries and inductors) that were generally employed for thermal ...
Characterizing the Roles of Exit Tunnel Residues in Ligand Binding and Catalysis of Histone Deacetylase-8
(North Dakota State University, 2014)
Histone deacetylases are an important class of enzymes that catalyze the hydrolysis of acetyl-L-lysine side chains in histone and non-histone proteins to yield L-lysine and acetate, effecting the epigenetic regulation of ...
Surface Chemistry Characterization of Hydrodesulfurization and Methanol Synthesis Model Nanocatalysts
(North Dakota State University, 2012)
Surface science investigations of model catalysts have contributed significantly to heterogeneous catalysis over the past several decades. The unique properties of nanomaterials are being exploited in catalysis for the ...
Identification of Active Sites in Heterogeneous Catalysis and Surface Chemistry Study of Alkanes Adsorption
(North Dakota State University, 2014)
Heterogeneous catalysis is considered the basis of the chemical industry. Surface science investigations on model catalysts have made significant contributions in gaining molecular level understanding of heterogeneously ...
New Strategies for Ruthenium Catalyzed C-C Bond Formation
(North Dakota State University, 2014)
Transition metal-catalyzed C-H bond activation allows direct functionalization of the ubiquitous C-H bonds in organic molecules to increase the molecular complexity. Since Murai's pioneering work in ruthenium catalyzed ...
Visual Detection of Cancer Biomarkers with Aptamer-Functionalized Gold Nanoparticles
(North Dakota State University, 2015)
Cancer biomarkers may hold the key for the early detection of cancer, distinguishing between benign and malignant cells, and differentiating tumor types. The detection of cancer biomarkers can be used for cancer diagnosis, ...
Novel Asymmetric Approaches for Construction of Small Molecules by Cyclization and Cycloaddition
(North Dakota State University, 2015)
Development of novel asymmetric and catalytic methods for synthesizing small organic
molecules containing hindered quaternary and tertiary centers is a major challenge and a
dynamic area of investigation in synthetic organic ...
Visible Light Photocatalysis of N-N Bond Based Compounds
(North Dakota State University, 2016)
The well-established principles of organic photochemistry, offer chemists the fundamental understanding and tools for studying light induced chemical transformations. Employing visible light for photocatalysis, one can ...
Stereospecific Phototransformations of Atropisomeric Chromophores
(North Dakota State University, 2014)
Photochemical transformations are unique strategy in synthesis that enables us to
access complex and structurally diverse organic scaffolds. However, the challenges in controlling
the excited-state to perform stereoselective ...