Chemistry & Biochemistry: Recent submissions
Now showing items 21-40 of 90
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Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling Reaction of Aromatic Esters and Aromatic Diesters with Arylboronic Acids
(North Dakota State University, 2020)The palladium-catalyzed cross-coupling reactions for the functionalization of the ester bond provides a significant overall improvement in the catalytic system as compared to aryl halides/pseudo-halides electrophilic ... -
Seeing the Forest for the Trees: An Exploration of Student Problem Solving and Reasoning with 1H NMR Spectral Features
(North Dakota State University, 2020)Nuclear magnetic resonance (NMR) spectroscopy is vital to synthesis and provides rich problem-solving opportunities for organic chemistry students. However, little is known about 1H NMR spectroscopy instruction or how ... -
Influence of Organic and Inorganic Passivation on the Photophysics of Cadmium Chalcogenide and Lead Chalcogenide Quantum Dots
(North Dakota State University, 2020)Quantum dots (QDs) are promising materials for photovoltaic (PV) and light-emitting diode (LED) applications due to their unique properties: photostability, size-tunable absorptivity, and narrow line-width emission. These ... -
New Strategies for Transition Metal Catalyzed C-C and C-N Bond Formation
(North Dakota State University, 2018)Transition metal catalysis emerged as an essential tool in the field of organic chemistry. In this context, transition metal catalyzed C-H bond functionalization is considered as an alluring strategy as it occurs with the ... -
Synthesis and Design of Thiophene Materials: Effects of Ring Fusion and Metal Coordination
(North Dakota State University, 2019)Conjugated organic materials comprise a field of materials chemistry focused on the development of semiconducting organic plastics, popular applications of which are plastic solar cells and display technologies. One of the ... -
Structural Basis for the Regulation of a Conserved TonB-dependent Iron Transport System via Cell-surface Signaling in Gram-negative Bacteria
(North Dakota State University, 2017)Cell-surface signaling (CSS) pathways are highly conserved systems in Gram-negative bacteria that allow the cell to efficiently respond to environmental stimuli through transcriptional regulation. Three distinct proteins ... -
Understanding the Interaction Between Enzymes and Nanomaterials
(North Dakota State University, 2019)The rapid development of nanoparticles (NPs) has impacted many fields including energy efficiency, material science, biosensing, and medical therapeutics. Recently, NPs have been utilized to immobilize enzymes. The so-formed ... -
Synthesis, Photophysics, Reverse Saturable Absorption, and Photodynamic Therapy of Iridium(III) Complexes Bearing Different Degrees of p-conjugation on the Ligands
(North Dakota State University, 2019)Octahedral d6 iridium(III) complexes possess rich photophysical properties. The most distinct phtotphysical properties of the Ir(III) complexes are their high triplet excited-state formation quantum yields, long-lived ... -
Development of Quantitative Lateral Flow Strip Biosensors for the Detection of Cancer Biomarkers
(North Dakota State University, 2019)The detection of cancer biomarkers is of great importance in oncology. Cancer biomarkers can provide diagnostic information which can aid disease screening and early diagnosis. Further, cancer biomarkers can help predict ... -
Investigating Selected Mechanisms of Modulation of BECN1-mediated Autophagy
(North Dakota State University, 2019)Autophagy is a lysosomal degradation pathway wherein cytoplasmic components not needed by or harmful to the cell are degraded and recycled. BECN homologs are key autophagy proteins consisting of an intrinsically disordered ... -
The Optimization of Whole Genome Amplification and Molecular Crowding for Use in Forensic Low Copy Number Samples
(North Dakota State University, 2011)Whole genome amplification has been used as a powerful tool to increase the amount of DNA template used for microarrays, STR and SNP assays in clinical and forensic settings. Our laboratory observed that multiple displacement ... -
Apoptosis-Inducing Factor Mediates Metabolism and Oxidative Stress Signaling through Functionally Uncoupled Mechanisms to the Benefit of Tumorigenesis
(North Dakota State University, 2019)Cancer is one of the leading causes of death in the world, arising when cells accumulate genomic mutations that render them incapable of controlling their own proliferation and survival. While substantial improvements in ... -
Acyl Imidazole : A Promising Template for Asymmetric Lewis and Brønsted Acid Mediated 1,3-Dipolar Cycloadditions
(North Dakota State University, 2011)Construction of chiral complex molecules continues to be a challenge for organic chemists all over the world and to address this challenge numerous methodologies have been developed. 1,3-Dipolar cycloaddition reactions is ... -
Fundamental Surface Properties and Gas-Surface Interactions of Two-Dimensional Materials
(North Dakota State University, 2019)Heterogeneous model catalysis with supported nanomaterials on ultra-thin two-dimensional films has contributed significantly to improve the existing industrial catalytic processes, as well as to discover novel ways to ... -
The Development and Use of Chiral 4-Dimethylaminopyridine-N-Oxide as an Organocatalyst
(North Dakota State University, 2018)Organocatalysis is a field that has bloomed over the last decades. With the field’s promise of being able to mimic nature and afford products in a synergistic manner to traditional Lewis acid catalysis, several interesting ... -
Synthesis and Applications of Dialdehydes
(North Dakota State University, 2018)Due to their reactivity and ease of functional group interconversions, aldehydes have wide-ranging applications in polymer synthesis, such as polyacetals, epoxy resins, and polyurethanes. Recently, room temperature synthesis ... -
Synthesis of Precursors to Non-isocyanate Polyurethanes
(North Dakota State University, 2018)Biobased diamines are excellent precursors for the synthesis of non-isocyanate polyurethanes (NIPUs). We have prepared several biobased diamines using three different reactions for their synthesis. In the first method, we ... -
Thiazole vs. Thiophene: Heterocycle Effects on the Properties of Fused-Ring Conjugated Materials
(North Dakota State University, 2017)Conjugated polymers and related molecular materials comprise a field of materials chemistry focused on the development of semiconducting organic plastics that find use in applications such as organic solar cells and organic ... -
Functionalization of Heterocycles: A Metal Catalyzed Approach via Allylation and C-H Activation
(North Dakota State University, 2018)The central core of many biologically active natural products and pharmaceuticals contain N-heterocycles, the installation of simple/complex functional groups using C-H/N-H functionalization methodologies has the potential ... -
Achiral Templates in Asymmetric Catalysis: Applications in Construction of All Carbon Quaternary Centers
(North Dakota State University, 2018)Conjugated olefins are readily available and inexpensive starting materials and their functionalization offers a rapid access to many important building blocks for organic synthesis. The functionalization of these olefins ...