Chemistry & Biochemistry: Recent submissions
Now showing items 61-80 of 90
-
Applications of Dithieno [3,2-B2',3'-D] Pyrroles and its Analogues to Conjugated Materials
(North Dakota State University, 2014)The promise of semiconducting materials with tunable electronic and optical properties that share the same mechanical flexibility, low production costs and ease of processing displayed by traditional polymers fuels the ... -
Identification of Active Sites in Heterogeneous Catalysis and Surface Chemistry Study of Alkanes Adsorption
(North Dakota State University, 2014)Heterogeneous catalysis is considered the basis of the chemical industry. Surface science investigations on model catalysts have made significant contributions in gaining molecular level understanding of heterogeneously ... -
Synthesis and Characterization of 2,3-Difunctionalized Thieno[3,4-b]Pyrazine-Based Terthienyls Structure-Function Relationships and Side Chain Tunability
(North Dakota State University, 2014)The ability to tune the physical, electronic, and optical properties of polymer precursors has garnered a great deal of interest in the conjugated organic materials field. The Rasmussen group has previously demonstrated ... -
Biophysical Studies of Ligand Binding to Human Histone Deacetylase-8
(North Dakota State University, 2014)Due to an involvement in various patho-physiological conditions, human histone deacetylases (HDACs) are high priority drug targets for the treatment of several diseases, such as cancer, heart failure, neurodegeneration, ... -
Enhanced Sensitivity of Lateral Flow Strip Biosensors Based on Enyzmatic Reaction and Nanomaterials
(North Dakota State University, 2014)Ultrasensitive detection for trace amount of proteins plays pivotal role in the diagnosis of specific diseases in clinical application, basic discovery research and the improvement of proteomics. Recently, lateral flow ... -
New Strategies for Ruthenium Catalyzed C-C Bond Formation
(North Dakota State University, 2014)Transition metal-catalyzed C-H bond activation allows direct functionalization of the ubiquitous C-H bonds in organic molecules to increase the molecular complexity. Since Murai's pioneering work in ruthenium catalyzed ... -
Identification of Novel RPA-Protein Interactions Using the Yeast Two Hybrid Assay and Identification of Regions Important for Interaction Between RPA and Rad24
(North Dakota State University, 2013)Replication Protein A (RPA) [Replication Factor A (RFA) in yeast] is an ssDNA binding protein composed of Rpa1, Rpa2, and Rpa3 and involved in numerous DNA processing pathways such as Replication, Recombination, and Repair. ... -
Exciton Diffusion, Transport, and Localization in Conjugated Polymers
(North Dakota State University, 2013)Conjugated polymers are wide bandgap semiconductors which have a series of conjugated π-orbitals that extend along the polymer ‘backbone’. The π-orbital conjugation can be disrupted by twisting of the polymer, affecting ... -
Stereospecific Photochemical Transformations Involving Axially Chiral Acrylanilides and a-Oxoamides
(North Dakota State University, 2013)Asymmetric photochemical transformations have been under-explored due to the ineffectiveness of conventional methodologies/reagents/catalysts (point chiral auxiliaries and inductors) that were generally employed for thermal ... -
Synthesis, Photophysics, and Nonlinear Absorption of Platinum (II) and Iridium (III) Complexes
(North Dakota State University, 2013)Square planar d8 platinum(II) complexes and octahedral d6 iridium(III) complexes were synthesized. Their photophysics were studied in detail. Structure-property relationship was studied by varying the substitution on the ... -
Synthesis, Characterization, and Application of Low and Reduced Band Gap Thieno[3,4-b]pyrazine-based Materials
(North Dakota State University, 2013)Conjugated polymers are a class of materials receiving significant interest due to their unique combination of optical and electronic properties found in inorganics with the flexibility and processability of traditional ... -
Attempted Total Syntheses of a Novel Lycopodine-Class Alkaloid and (R)-Myricanol, Compounds for the Treatment of Alzheimer's Disease
(North Dakota State University, 2013)Alzheimer's Disease (AD) is a significant challenge to both the pharmaceutical world as well as the synthetic organic chemistry world. One of the most important problems in this field is the lack of a unified approach to ... -
Mechanistic Studies on the Methionine Aminopeptidase and Peptide Deformylase Catalyzed Reactions
(North Dakota State University, 2013)In the search for novel antibiotic and therapeutic targets, methionine aminopeptidase (MetAP) and peptide deformylase (PDF) have recently been identified as eminently compelling. These enzymes are involved in the ... -
Supramolecular Functionalization of Single-Walled Carbon Nanotubes
(North Dakota State University, 2013)Single-walled carbon nanotubes (SWNTs) possess extraordinary mechanical strength, thermal and electrical conductivity. These properties make them very attractive in many applications in the fields of nanotechnology, ... -
Developing Platform Chemicals from Renewable Resources
(North Dakota State University, 2013)The Department of Energy has listed 5-hydroxymethylfurfural (HMF) and 2,5-furandicarboxylic acid (FDCA) as two of the twelve building blocks derived from cellulosic biomass. HMF can serve as a renewable platform for the ... -
Surface Chemistry Characterization of Hydrodesulfurization and Methanol Synthesis Model Nanocatalysts
(North Dakota State University, 2012)Surface science investigations of model catalysts have contributed significantly to heterogeneous catalysis over the past several decades. The unique properties of nanomaterials are being exploited in catalysis for the ... -
From Nanocontainer to Nanocatalyst: Mechanistic Studies of [2+2] Photodimerization of Coumarin Derivatives within Cucubit[8]URIL
(North Dakota State University, 2013)Controlling photoreactions remains a formidable challenge to chemists who have developed several approaches with varying degrees of success to achieve high reactivity/selectivity. Following nature's footprints, chemists ... -
Biological Effects of Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase Activating Polypeptide Receptor 1 (VPAC1) and VPAC2 on Chemotaxis and its Regulation of the Tumor Suppressor Ikaros in Leukemic T Cells
(North Dakota State University, 2012)One in three children diagnosed with cancer has leukemia. Leukemia patients with mutations in the tumor suppressor transcription factor Ikaros (IK), an anti-leukemic factor that is critical for the development of blood ... -
Stereoselective Carbon-Carbon Bond Construction Using Indium and Bismuth: New Methods in Green Chemistry
(North Dakota State University, 2012)Selective chemical reactions that can be accomplished with minimal waste using non-toxic catalysts and reagents will allow for new greener chemical processes for future environmentally sustainable technologies. This work ... -
Ultrasensitive Lateral Flow Nucleic Acid Biosensors Based on Novel Macro-/Nano-Materials
(North Dakota State University, 2017)Video summarizing a Ph.D. dissertation for a non-specialist audience.